Objective:
@EN To scrutinize nutritional assessment in patients undergoing hemodialysis, we calculated the dose of dialysis(Kt/V) and normalized protein catabolic rate(NPCR) with urea kinetic modeling and analyzed the relationship between NPCR and other
biochemical nutritional parameters
@EN Methods and Materials:
@EN We selected 40 patients undergoing maintenece hemodialysis, twice(n=7) or three times(n=23) a week, from January 1993 to December 1994. We checked the biochemical nutritional parameters such as serum albumin, BUN, potassium, phosphorus,
creatinine,
and cholesterol levels every month, and calculated their mean values during study periods.
@ES Results:
@EN 1) The mean value of serum cholesterol, BUN, creatinine, potassium, phosphorus, albumin levels was 148.14±5.83mg/dL, 74.06±2.4mg/dL, 10.8±0.51mg/dL, 5.43±0.08mEq/L, 4.95±0.21mg/dL, 4.05±0.06g/dL, respectively, Also, that of NPCR was
0.88±0.03g/kg/day. In 26% of patients, NPCR was less than 0.8g/kg/day.
2) NPCR correlated with serum BUN(r=0.862, p<0.0001), potassium(r=0.467, p<0.01), and phosphorus levels(r=0.571, p<0.0001). Serum cholesterol, creatinine, and albumin levels did not correlate with NPCR
3) NPCR correlated with weekly-Kt/V(r=0.413, p<0.01), but not with Kt/V and URP
4) Diabetes(or non-diabetes), sex(male or female), age, schedule(3x/week of 2x/week), duration, dialysates(bicarbonate or acetate), dialyzer blood flow, total minutes per session, or mean arterial pressure did not correlate with NPCR
5) Serum albumin levels showed positive correlation with serum creatinine levels(r=0.514, p<0.01)
@ES Conclusion:
@EN Semm BW, potassium, phosphms, weekly-Kt/V, creatine, and albumin levels can be used as an adjunctive parameters to NPCR in the nutritional assessment of chronic renal failure patients undergoing hemodialysis.
|